In 2015 the UN General Assembly included a specific target for cities and local communities (n. 11) in the Sustainable Development Goals (SDGs), thus recognizing urbanisation as a major global challenge. Today, the role of global cities is put to the test by the Covid-19 pandemic. The need for a urgent and coherent management of the emergency also in urban realities – not to mention slums – places further emphasis on the quest for sustainable urbanisation processes and strategies worldwide. How to achieve these goals? What is the expected impact of Covid-19 on SDGs targets on sustainable urbanisation? Will it be a further constraint or will it help meet the targets? And where to look for best practices?